prefrontal cortex
noun
: the gray matter of the anterior part of the frontal lobe that is highly developed in humans and plays a role in the regulation of complex cognitive, emotional, and behavioral functioning
Examples of prefrontal cortex in a Sentence
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College students are easily susceptible to betting, Warner said, as their prefrontal cortex – the part of the brain responsible for impulse control and decision‑making – is still developing.
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Lance Reynolds, Boston Herald, 9 Jan. 2026
The system delivers low-intensity transcranial direct-current stimulation (tDCS) to the prefrontal cortex – a region of the brain that exhibits diminished activity in many people suffering from depression.
—New Atlas, 4 Jan. 2026
Like the vast majority of people in their early 20s, my prefrontal cortex hadn’t fully developed.
—Eddie Brown, San Diego Union-Tribune, 20 Dec. 2025
Devices like Exomind, a form of Transcranial Magnetic Stimulation (TMS), target the brain’s dorsolateral prefrontal cortex—the center of executive function, mood regulation, and attention.
—Emily Cegielski, Flow Space, 9 Dec. 2025
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Lance Reynolds, Boston Herald, 9 Jan. 2026
The system delivers low-intensity transcranial direct-current stimulation (tDCS) to the prefrontal cortex – a region of the brain that exhibits diminished activity in many people suffering from depression.
—New Atlas, 4 Jan. 2026
Like the vast majority of people in their early 20s, my prefrontal cortex hadn’t fully developed.
—Eddie Brown, San Diego Union-Tribune, 20 Dec. 2025
Devices like Exomind, a form of Transcranial Magnetic Stimulation (TMS), target the brain’s dorsolateral prefrontal cortex—the center of executive function, mood regulation, and attention.
—Emily Cegielski, Flow Space, 9 Dec. 2025
See All Example Sentences for prefrontal cortex
Cite this Entry
“Prefrontal cortex.” Merriam-Webster.com Dictionary, Merriam-Webster, https://www.merriam-webster.com/dictionary/prefrontal%20cortex. Accessed 14 Jan. 2026.
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